I try to keep it simple
1 PC, screens(3x) left(22in), center(32in2.5k) and side left(19in)
1 Mac, screens(2x) right(22in) and top(22in)
1 iPad Pro, bottom left
I use one keyboard and mouse to control 'em all using "Synergy" or the open source version now called "Barrier"
I've hacked the slider on the M-Audio 88, and reassigned it to the pitch wheel by cutting the spring, so CC11 to the left, CC1 the right. Best move ever.
Back of the room is a perfect rectangle, 20ft deep by 10ft wide
All the machines are in the basement on the floor below through a routing hole, so no noise whatsoever
They all hang from a rack I made on the top of the ceiling so to minimize long cabling runs.
You will never know what my speaker monitors are because I made them myself, I don't believe in powered monitors you buy in the stores, they always have very very bad noise floor when nothing is actually playing. That's detrimental to my concentration... So I mod my own amps and use the crossovers I want in my speaker enclosures—changing speakers to what I want. I have ZERO noise when nothing is playing and that's so rewarding
[I was an electronics tech in another life]