Main Mac = MacBook Pro 2014 Retina w/16 GB RAM
(4) SSDs in an OWC TB chassis (2 project drives, 2 samples)
(2) UA Apollos, Philips 40" 4k monitor all via TB
Running OSX 10.11.3, Logic X 10.3.1
VE Pro (32 bit) running EastWest Play for older perc libraries
VE Pro (64 bit) running (9) 16-channel Kontakt multis (144 instruments)
...mostly perc libraries, a bunch of misc. guitars & ethnic instruments
Slave 1 -
www.studiocat.com turnkey VE Pro PC slave (4.16 GHz quad i7, 64 GB RAM, 4 sample SSDs)
VE Pro running (28) 16-channel multis (Kontakt, PLAY) - 448 insts total, all demanding libraries; uses about 40 GB RAM fully loaded
Slave 2 - 2009 iMac Core2Duo, 16 GB RAM
VEP running 4 x 16ch older Kontakt libraries (64 insts total)
Slave 3 - 2012 Mac Mini quad i7, 16 GB RAM
VEP running 11 x 16ch Kontakt multis (176 insts total)
Slave 4 - 2010 MacBook Pro 2.28 Core2Duo
VEP running 8 x 16ch older Kontakt libraries (128 insts total)
So, that's 976 instruments loaded across all 5 machines, all in VE Pro 16-channel instances. I also run another ~100 EXS instruments in Logic, and then any project-specific stuff like Omnisphere, Nexus, other VIs, etc. As for processing, my template contains 8-12 effects buses: mostly reverb options (Lex PCM Random Hall, 2C B2, Slate VerbSuite Bricasti, NI RC48, some custom Space Designer stuff), and of course tons of EQ, compression as needed, etc.
All runs flawlessly!