OK, so my Omnisphere USB package arrived yesterday and I installed it.
After playing with it for a bit (while also trying to work and assist kids with remote learning) I've come to a few immediate conclusions:
1) Holy sh** I should have bought this earlier, maybe instead of a couple other sample instruments I bought during summer sales recently.
2) One of my favorite aspects is how every single patch has some informative text commentary, like how to get the most of that patch, or some background information on the sampled instrument. It really shows the time and effort put into the library.
3) Multis are a lot of fun
4) My Wavestate is feeling a bit jealous (though different tools), it's hard to compare 2GB of sample material vs. 60+ GB
5) The interface is very clean, doesn't overwhelm you with info you don't need. It looks "dated" in some respects but I wouldn't completely redo it, just add some more visual feedback perhaps but keep the layout the same. Pretty easy to get around if you know the basics of synthesis.
6) Multis are a ton of fun (again), latch mode is sweet, and the Orb is crazy
Minor complaints:
A small number of patches are throwing errors. Primarily guitar patches for some reason. I might have some corrupted files, I have emailed support.
Reface CS hardware integration isn't SUPER useful, and I actually like the sound from the hardware synth better than the Omnisphere version. Some of the controls don't do the same thing as the hardware because FM and Ring Mod aren't a 1-to-1 mapping. BUT you can assign multiple LFO's which you can't do with the hardware. I would rather have a much knobbier synth for hardware control (Roland SE02 would be nice).
Summary... an extremely impressive package, Alchemy no longer compares, and I have no excuse not to be writing music except that I keep just endlessly messing with presets!