ahhh, sorry, i missed that part of the thread.I get the impression that most of this discussion has centered on using amp sims with real, physical guitars. The OP asked about using sims with virtual instrument guitars, which would tend to interact differently than real instruments. Having read the entire thread, I didn’t see much of anything specific to that (although I got a lot of useful information about death metal dual guitars that may prove useful at some point).
If I’m wrong or missing important points from the discussion, please tell me. But, to the OP’s question, what are you finding particularly effective with VI guitars?
i don't use VI guitars, but i would think some of the SIMs listed would work equally well.
but, i'll stop posting.